68 research outputs found
PrĂ©valence et facteurs de risque d'obĂ©sitĂ© et de surpoids dans une population de chiens sains prĂ©sentĂ©s en mĂ©decine prĂ©ventive Ă lâĂcole Nationale VĂ©tĂ©rinaire de Toulouse et Ă lâĂcole Nationale VĂ©tĂ©rinaire de Maisons-Alfort
Lâobjectif de cette Ă©tude, menĂ©e entre Septembre et Juillet 2021, Ă©tait de dĂ©terminer la prĂ©valence et les facteurs de risque dâexcĂšs pondĂ©ral dans une population de chiens sains prĂ©sentĂ©s en consultation de mĂ©decine prĂ©ventive dans les Ăcoles Nationales VĂ©tĂ©rinaires de Toulouse et Maisons Alfort. Les informations sur le mode de vie et les habitudes alimentaires ont Ă©tĂ© rĂ©coltĂ©es grĂące Ă un questionnaire. LâĂ©tat corporel et musculaire a Ă©tĂ© Ă©valuĂ©, par le personnel formĂ©, puis comparĂ© aux notes attribuĂ©es par le propriĂ©taire. Les prĂ©valences de surpoids et dâobĂ©sitĂ© ont Ă©tĂ© de 33,9% et de 2,3%. Le risque dâexcĂšs pondĂ©ral augmente avec lâĂąge (OR=3,7 pour la classe dâĂąge 7 Ă 12 ans ; p<0,001), chez les femelles (OR=2,4 ; p<0,001), les chiens stĂ©rilisĂ©s (OR=2,56 ; p<0,05), ceux rarement vermifugĂ©s (OR=6,6 ; p<0,05) et diminue quand lâaliment est achetĂ© en clinique vĂ©tĂ©rinaire (OR=0,17 ; p<0,001). Une tendance Ă la sous-estimation du score corporel par les propriĂ©taires a Ă©tĂ© observĂ©e
En attendant « le jour [âŠ] oĂč il n\u27y aura plus de catalogue Ă faire » : une histoire matĂ©rielle des catalogues de bibliothĂšque (1789 â 1993)
MĂ©moire de fin d\u27Ă©tude du diplĂŽme de conservateur, promotion 22 portant sur l\u27histoire des catalogues des bibliothĂšques
Dynamic proofs of retrievability with low server storage
Proofs of Retrievability (PoRs) are protocols which allow a client to store
data remotely and to efficiently ensure, via audits, that the entirety of that
data is still intact. A dynamic PoR system also supports efficient retrieval
and update of any small portion of the data. We propose new, simple protocols
for dynamic PoR that are designed for practical efficiency, trading decreased
persistent storage for increased server computation, and show in fact that this
tradeoff is inherent via a lower bound proof of time-space for any PoR scheme.
Notably, ours is the first dynamic PoR which does not require any special
encoding of the data stored on the server, meaning it can be trivially composed
with any database service or with existing techniques for encryption or
redundancy. Our implementation and deployment on Google Cloud Platform
demonstrates our solution is scalable: for example, auditing a 1TB file takes
just less than 5 minutes and costs less than $0.08 USD. We also present several
further enhancements, reducing the amount of client storage, or the
communication bandwidth, or allowing public verifiability, wherein any
untrusted third party may conduct an audit
Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis
BACKGROUND: New diagnosis tests are urgently needed to address the global tuberculosis (TB) burden and to improve control programs especially in resource-limited settings. An effective in vitro diagnostic of TB based on serological methods would be regarded as an attractive progress because immunoassays are simple, rapid, inexpensive, and may offer the possibility to detect cases missed by standard sputum smear microscopy. However, currently available serology tests for TB are highly variable in sensitivity and specificity. Lipolytic enzymes have recently emerged as key factors in lipid metabolization during dormancy and/or exit of the non-replicating growth phase, a prerequisite step of TB reactivation. The focus of this study was to analyze and compare the potential of four Mycobacterium tuberculosis lipolytic enzymes (LipY, Rv0183, Rv1984c and Rv3452) as new markers in the serodiagnosis of active TB. METHODS: Recombinant proteins were produced and used in optimized ELISA aimed to detect IgG and IgM serum antibodies against the four lipolytic enzymes. The capacity of the assays to identify infection was evaluated in patients with either active TB or latent TB and compared with two distinct control groups consisting of BCG-vaccinated blood donors and hospitalized non-TB individuals. RESULTS: A robust humoral response was detected in patients with active TB whereas antibodies against lipolytic enzymes were infrequently detected in either uninfected groups or in subjects with latent infection. High specifity levels, ranging from 93.9% to 97.5%, were obtained for all four antigens with sensitivity values ranging from 73.4% to 90.5%, with Rv3452 displaying the highest performances. Patients with active TB usually exhibited strong IgG responses but poor IgM responses. CONCLUSION: These results clearly indicate that the lipolytic enzymes tested are strongly immunogenic allowing to distinguish active from latent TB infections. They appear as potent biomarkers providing high sensitivity and specificity levels for the immunodiagnosis of active TB
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
« Agua de rosas » de Lila Downs : une expérience de vision
Dans son album Entre copa y copa, canciones de cantina(2006), Lila Downs, une artiste mexico-Ă©tatsunienne de musique du monde, propose une composition intitulĂ©e « Agua de rosas », dans laquelle lâartiste prend pour thĂšme le bain de roses que des guĂ©risseuses zapotĂšques de JuchitĂĄn de Zaragoza, dans lâEtat dâOaxaca, Mexique, lui ont donnĂ© pour quâelle se dĂ©tende et soigne ses peines. Cette chanson correspond Ă©galement Ă un Ă©loge funĂšbre adressĂ© Ă Idalia Linares SĂĄnchez, une amie personnelle. Idalia Linares reprĂ©sentait un membre actif de la CoaliciĂłn Obrera, Campesina y Estudiantil del Istmo, une association indienne qui remporte les Ă©lections municipales de JuchitĂĄn en 1981. Un entretien avec la fille dâIdalia Linares, Marlene Linares, qui a notamment connu une expĂ©rience migratoire aux Etats-Unis, ainsi que le discours poĂ©tique de Lila Downs nous amĂšneront Ă nous interroger sur la vie et la subjectivitĂ© des femmes zapotĂšques, sur les continuitĂ©s et les ruptures entre deux gĂ©nĂ©rations, sur les tensions entre lâancien et le moderne.In her album Entre copa y copa, canciones de cantina (2006), Lila Downs, a Mexican-American artist of world music, proposes a composition entitled « Agua de rosas », a song in which the artist takes for topic the bath of roses that Zapotec healers of JuchitĂĄn de Zaragoza, in Oaxacaâs State in Mexico, gave her so that she relaxes and lightens hers sorrows. This song also corresponds to a funeral oration addressed to Idalia Linares SĂĄnchez, a personal friend. Idalia Linares represented an active member of the CoaliciĂłn Obrera, Campesina y Estudiantil del Istmo, an Indian association which wins JuchitĂĄnâs municipal elections in 1981. A discussion with Idalia Linaresâ daughter, Marlene Linares, which especially knew a migratory experiment in the United States, as well as Lila Downsâ poetic discourse will lead us to wonder about the life and the subjectivity of the Zapotec women, about continuities and ruptures between two generations, about the tensions between the ancient and the modern
La chanson populaire mexicaine : du bestiaire amusant au double sens
International audienc
Récits sur la folie : la légende mexicaine de la Llorona
Le mythe de la Llorona a inspirĂ© de nombreuses artistes et Ă©crivaines postmodernes hispano-amĂ©ricaines, qui ont converti cette Femme qui pleure mexicaine en une icĂŽne identitaire plus positive que dans la tradition orale classique. Cette approche Ă la fois intimiste et transnationale peut dĂ©jĂ sâobserver dans la littĂ©rature chicana des annĂ©es 80 et 90. Elle concerne dĂ©sormais Ă©galement des musiciennes telles que Lila Downs, chanteuse de musique du monde, ou des auteures issues dâautres groupes culturels, comme la chilienne Marcela Serrano (La Llorona, 2008)
Homenaje a BĂĄrbaro Teuntor GarcĂa
Hommage à  BĂĄrbaro Teuntor GarcĂa Homenaje a BĂĄrbaro Teuntor GarcĂa Larmes, tendresse, tempĂȘte LĂĄgrimas, ternura, tormenta Pas de mot, juste un vide No hay palabras, sĂłlo un vacĂo Ou un trop-plein qui sâarrĂȘte O un desbordamiento que se detiene Pour laisser place aux pleurs Para dejar lugar al llanto Quand on nâa pas assez aimĂ© Cuando uno no ha amado lo suficiente Le coup est rude, le goĂ»t, amer, El golpe es duro, el sabor, amargo, Mais le cĆur palpite encore Pero el corazĂłn aĂșn palpita Tand..
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